RWJ-56110 dihydrochloride - CAS# 2387505-58-8 Size:2mg solid Molecular Weight: 455

Molecular Weight: 455

3-dimethyl-2-oxo-2

67 mg/mL (142

Pharmacological characterization of a novel cannabinoid ligand

RWJ-56110 dihydrochloride - CAS# 2387505-58-8 Size:2mg solid Molecular Weight: 455RWJ 56110 dihydrochloride is a potent, selective, peptide mimetic inhibitor of PAR 1 activation and internalization (binding IC50=0. 44 uM) and shows no effect on PAR 2, PAR 3, or PAR 4. RWJ 56110 dihydrochloride inhibits the aggregation of human platelets induced by both SFLLRN NH2 (IC50=0. 16 M) and thrombin (IC50=0. 34 M), quite selective relative to U46619 (HY 108566). RWJ 56110 dihydrochloride blocks angiogenesis and blocks the formation of new